ncRNA name | hsa-miR-140-5p |
ncRNA Category | miRNA |
Disease name | autoimmune uveitis |
Species | Homo sapiens |
Tissues/Cell_line | serum |
Methods | TaqMan OpenArray, qRT-PCR, flow cytometry |
Expression pattern | up-regulated |
Functional description | miR-140-5p, which had the highest discriminative power between uveitis patients and controls, is aberrantly expressed and implicated in pathogenic T-cell function in multiple sclerosis, a disease linked to IU.we also noted associated pathways relevant for ocular biology, including VEGF signaling, photoreceptor development, and retina homeostasis. |
PubMed ID | 29435587 |
Year | 2018 |
Title | A Disease-Associated MicroRNA Cluster Links Inflammatory Pathways and an Altered Composition of Leukocyte Subsets to Noninfectious Uveitis. |
Drug-related ncRNA | NO |
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